Rigging issue in maya

Dear Sir/Ma`am,

I am facing several issues in rigging in Maya.

  1. Some bones are showing RED in colour ( L-R should to wrist & L-R Pelvis to Ankle). However apply applying IK both hands and legs movements found OK.

  2. Before parenting Wrist bone to hand controller circle, everything was fine but after parenting wrist bone to hand controller circle, ELBOW bone gets disappear.

Please guide me.